2022
ALDH2 variance in disease and populations. Chen CH, Kraemer BR, Mochly-Rosen D. Dis Model Mech. 2022 Jun 1;15(6):dmm049601. doi: 10.1242/dmm.049601. Epub 2022 Jun 24. PMID: 35749303; PMCID: PMC9235878.
Practical synthesis of the therapeutic leads tigilanol tiglate and its analogues. Wender PA, Gentry ZO, Fanelli DJ, Luu-Nguyen QH, McAteer OD, Njoo E.Nat Chem.2022 Oct 3. doi: 10.1038/s41557-022-01048-2. Epub ahead of print. PMID: 36192432.
Back To Top2019
Zinc-Chelating Small Molecules Preferentially Accumulate and Function within Pancreatic β Cells.
Horton TM, Allegretti PA, Lee S, Moeller HP, Smith M, Annes JP. Cell Chem Biol. 2019 Feb 21;26(2):213-222.e6. doi: 10.1016/j.chembiol.2018.10.019. Epub 2018 Dec 6.
Fluorescent Triazole Urea Activity‐Based Probes for the Single‐Cell Phenotypic Characterization of Staphylococcus aureus.
Linhai Chen Laura J. Keller Edward Cordasco, Matthew Bogyo, Christian S. Lentz. Angew Chem Int Ed. 2019, 58, 5643-5647
2018
CC-401 Promotes β-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition.
Abdolazimi Y, Lee S, Xu H, Allegretti P, Horton TM, Yeh B, Moeller HP, Nichols RJ, McCutcheon D, Shalizi A, Smith M, Armstrong NA, Annes JP. (2018) Endocrinology. 2018 Sep 1;159(9):3143-3157. doi: 10.1210/en.2018-00083. PubMed PMID: 29514186.
Protein-Based Inheritance: Epigenetics beyond the Chromosome.
Zachary H Harvey, Yiwen Chen, Daniel F Jarosz. Molecular Cell. 2018 Jan 18;69(2): 195-202. PMID: 29153393. PMCID: PMC5775936.
Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo.
Kornfeld OS, Qvit N, Haileselassie B, Shamloo M, Bernardi P, and Mochly-Rosen D. Sci Rep. 2018 Sept 19;8(1):14034. PMID: 30232469. PMCID: PMC6145916.
2017
Protein-Based Inheritance: Epigenetics Beyond The Chromosome.
Harvey ZH, Chen Y, Jarosz DF. (2017) Mol Cell. 2017 Nov 15. pii: S1097-2765(17)30807-9. doi: 10.1016/j.molcel.2017.10.030. Review.
2016
Engineered substrate-specific delta PKC antagonists to enhance cardiac therapeutics.
Qvit N, Kornfeld OS, Mochly-Rosen D. (2016) Angew Chem Int Ed Engl. 2016 Dec 12. doi: 10.1002/anie.201605429.
Correcting mitochondrial fusion by manipulating mitofusin conformations.
Franco A, Kitsis RN, Fleischer JA, Gavathiotis E, Kornfeld OS, Gong G, Biris N, Benz A, Qvit N, Donnelly SK, Chen Y, Mennerick S, Hodgson L, Mochly-Rosen D, Dorn GW II. (2016) Nature. 2016 Dec 1. doi: 10.1038/nature20156.
The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained.
Joshi AU, Kornfeld OS, Mochly-Rosen D. (2016) Cell Calcium. 2016 Sep. doi: 10.1016/j.ceca.2016.04.010.
Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation.
Qvit N, Kornfeld OS. (2016) J Vis Exp. 2016 Jan 26. doi: 10.3791/53589.
2015
Mitochondrial reactive oxygen species at the heart of the matter: new therapeutic approaches for cardiovascular diseases.
Kornfeld OS, Hwang S, Disatnik MH, Chen CH, Qvit N, Mochly-Rosen D. (2015) Circ Res. 2015 May 22. doi: 10.1161/CIRCRESAHA.116.305432.